Propionibacterium acnes or P. acnes, is a bacteria involved in the development of acne lesions. For years topical antibiotics such as erythromycin or clindamycin have been recommended as a part of acne therapy to combat this bacteria; however increased concern has risen due to the emerged resistance of P. acnes to this type of drugs.

Topical benzoyl peroxide is an alternative of topical antibiotics, it is not expensive and doesn’t create resistance. However some people cannot tolerate its side effects which include skin irritation, peeling, itching, and redness.

The development of topical nitric oxide may provide with an alternative to topical antibiotics. Nitric oxide is naturally synthesized by the human body in response to bacteria, it has a low propensity for resistance and it could even reduce sebum production.

Results of studies made with this component are going to be presented in the World Congress of Dermatology this year.


Acne is a common condition that affects 80% of adolescents and young adults from the ages of 11 to 30. However the common belief that you will soon outgrow the disease is not always correct. It’s been reported that around 42.5% of men and 50.9% of women continue to suffer from this condition into their adulthood.

It’s location upon the face is apt to be a possible source of great annoyance and embarrassment, not only just to teenagers but also to young adults.

Although acne lacks the urgency of a life-threatening condition, it produces long term ramifications that can be coming up with cutaneous and emotional scars lasting lifetime. It debilitates an individual’s confidence causing physical, social, and psychological sufferings and reduces self-esteem.

What causes acne?

Certain facts are known about acne: the primary factors involved in the onset of acne are increased sebum production, abnormal keratinization, inflammation, and bacterial colonization by Propionibacterium acnes. However it is considered that acne is not an infectious disease, it’s more an inflammatory process and the role of P. acnes is more inflammatory than infectious.

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